Study Purpose:

This research is being done to identify what factors help kidneys stay healthy or cause a decline in kidney function, and also to see how kidney problems affect aspects of health and wellbeing.


Study Summary:

The CKiD Study is a NIH-funded, multicenter, prospective cohort study of children aged 1 to 16 years with mild to moderate impaired kidney function. The primary goals of CKiD are to determine the risk factors for decline in renal function and to define how progressive decline in renal function impacts biomarkers of risk factors for cardiovascular disease; neurocognitive function and behavior; and growth failure and its associated morbidity.


Basic Eligibility Criteria:

Basic eligibility criteria for the study include subjects who are between the ages of 6 months and 16 years old who are willing and able to provide informed consent/assent.  Eligible subjects include those with a non-glomerular diagnosis and duration of kidney disease less than 5 years will be enrolled and with serum creatinine ≥ 0.5 mg/dl as well as two or more of the following:

significant proteinuria (urine protein to creatinine ratio > 0.2),
persistent urinary sediment abnormalities (at least 3  months),
evidence of renal tubular disorders or
pathologic abnormalities detected by histology or imaging 


Study Location(s):

Phoenix Children’s Hospital

1919 E. Thomas Road

Phoenix, AZ 85016


Study Contact(s):

Jessica Twyford



Heather Shearer


Share this page: